文献类型： 外文期刊
作者： Li, Bing 1 ; Zhang, Bo 2 ; Zhang, Fuli 1 ; Liu, Xiaomeng 1 ; Zhang, Yunxia 1 ; Peng, Weifeng 1 ; Teng, Da 3 ; Mao, Ruoyu 3 ; Yang, Na 3 ; Hao, Ya 3 ; Wang, Jianhua 3 ;
作者机构： 1.Zhoukou Normal Univ, Inst Translat Med, Coll Life Sci & Agron, Zhoukou 466001, Henan, Peoples R China
2.Zhoukou Normal Univ, Int Joint Res Lab Biomed Nanomat Henan, Zhoukou 466001, Henan, Peoples R China
3.Chinese Acad Agr Sci, Feed Res Inst, Gene Engn Lab, Beijing 100081, Peoples R China
4.Minist Agr & Rural Affairs, Key Lab Feed Biotechnol, Beijing 100081, Peoples R China
关键词： lactoferrin; gut microbiota; host health; interaction; noncommunicable chronic diseases
期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：6.1； 五年影响因子：6.3 ）
ISSN： 0021-8561
年卷期： 2024 年 72 卷 14 期
页码：
收录情况： SCI
摘要： The gut microbiota are known to play an important role in host health and disease. Alterations in the gut microbiota composition can disrupt the stability of the gut ecosystem, which may result in noncommunicable chronic diseases (NCCDs). Remodeling the gut microbiota through personalized nutrition is a novel therapeutic avenue for both disease control and prevention. However, whether there are commonly used gut microbiota-targeted diets and how gut microbiota-diet interactions combat NCCDs and improve health remain questions to be addressed. Lactoferrin (LF), which is broadly used in dietary supplements, acts not only as an antimicrobial in the defense against enteropathogenic bacteria but also as a prebiotic to propagate certain probiotics. Thus, LF-induced gut microbiota alterations can be harnessed to induce changes in host physiology, and the underpinnings of their relationships and mechanisms are beginning to unravel in studies involving humans and animal models.
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