文献类型： 外文期刊
作者： Liu, Beibei 1 ; Chen, Ge 1 ; Abd El-Aty, A. M. 3 ; Zhai, Rongqi 1 ; Liu, Guangyang 1 ; Xu, Xiaomin 1 ; Zhang, Yanguo 1 ; Li, Lingyun 1 ; Zhang, Jie 2 ; Xu, Donghui 1 ;
作者机构： 1.CAAS, Minist Agr & Rural Affairs China,Inst Vegetables F, Minist Agr Vegetable Prod Qual Safety Risk Assessm, Key Lab Vegetable Qual & Safety Control,State Key, Beijing 100081, Peoples R China
2.Beijing Univ Agr, Coll Plant Sci & Technol, Beijing 102206, Peoples R China
3.Cairo Univ, Fac Vet Med, Dept Pharmacol, Giza 12211, Egypt
4.Ataturk Univ, Fac Med, Dept Med Pharmacol, TR-25240 Erzurum, Turkiye
关键词： Functional nucleic acids; Specific recognition; Application
期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.5； 五年影响因子：8.7 ）
ISSN： 0141-8130
年卷期： 2025 年 304 卷
页码：
收录情况： SCI
摘要： Nucleic acids, which are fundamental to living organisms, play a crucial role in carrying and transmitting genetic information. Advances in molecular biology have led to the exploration of functional nucleic acids (FNAs), including aptamers, DNAzymes, and G-quadruplexes, known for specific recognition or catalysis. FNAs with high specificity, sequence programmability, modification ease and biocompatibility, have extensive applications in biosensing, environmental monitoring, drug delivery and cancer diagnosis. This review focuses on the structure and specific recognition principles of FNAs, followed by an exploration for biosensing and biomedical applications, offering insights into current challenges and future trends in FNAs as recognition elements.
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