A Genome-Wide Analysis of Serine Protease Inhibitors in Cydia pomonella Provides Insights into Their Evolution and Expression Pattern
文献类型: 外文期刊
第一作者: Wu, Qiang
作者: Wu, Qiang;Huang, Cong;Liu, Bo;Wan, Fanghao;Qian, Wanqiang;Xing, Longsheng;Du, Min;Zhou, Hongxu;Liu, Wanxue
作者机构:
关键词: serine protease inhibitor; melanization; Cydia pomonella; innate immunity; alternative splicing
期刊名称:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES ( 影响因子:5.6; 五年影响因子:6.2 )
ISSN: 1661-6596
年卷期: 2023 年 24 卷 22 期
页码:
收录情况: SCI
摘要: Serine protease inhibitors (serpins) appear to be ubiquitous in almost all living organisms, with a conserved structure and varying functions. Serpins can modulate immune responses by negatively regulating serine protease activities strictly and precisely. The codling moth, Cydia pomonella (L.), a major invasive pest in China, can cause serious economic losses. However, knowledge of serpin genes in this insect remain largely unknown. In this study, we performed a systematic analysis of the serpin genes in C. pomonella, obtaining 26 serpins from the C. pomonella genome. Subsequently, their sequence features, evolutionary relationship, and expression pattern were characterized. Comparative analysis revealed the evolution of a number of serpin genes in Lepidoptera. Importantly, the evolutionary relationship and putative roles of serpin genes in C. pomonella were revealed. Additionally, selective pressure analysis found amino acid sites with strong evidence of positive selection. Interestingly, the serpin1 gene possessed at least six splicing isoforms with distinct reactive-center loops, and these isoforms were experimentally validated. Furthermore, we observed a subclade expansion of serpins, and these genes showed high expression in multiple tissues, suggesting their important roles in C. pomonella. Overall, this study will enrich our knowledge of the immunity of C. pomonella and help to elucidate the role of serpins in the immune response.
分类号:
- 相关文献
作者其他论文 更多>>
-
Testing a biocontrol agent consortium for suppression of tomato bacterial wilt through rhizosphere microecological regulation
作者:Zheng, Xuefang;Wang, Jieping;Chen, Meichun;Chen, Yanping;Chen, Zheng;Liu, Bo;Wang, Mingkuang
关键词:Bacterial wilt; Biocontrol control agent consortium; Microecological regulation; Ralstonia solanacearum; Rhizosphere
-
Establishment and characterization of a muscle cell line from golden pompano (Trachinotus ovatus) and its application in viral susceptibility
作者:Zhang, Lu-Ke;Zhu, Ke-Cheng;Guo, Hua-Yang;Liu, Bao-Suo;Liu, Bo;Zhang, Nan;Zhang, Dian-Chang;Zhang, Lu-Ke;Zhang, Lu-Ke;Zhu, Ke-Cheng;Guo, Hua-Yang;Liu, Bao-Suo;Liu, Bo;Zhang, Nan;Zhang, Dian-Chang;Zhang, Dian-Chang
关键词:Trachinotus ovatus; Muscle; Cell line; Red-spotted grouper nervous necrosis virus; Immunity
-
Patterns and determinants of nitrification and denitrification potentials across 24 rice paddy soils in subtropical China
作者:Wang, Jun;Zhang, Wenju;Wu, Lei;Lv, Lu;Hu, Ronggui;Ma, Haiyang;Liu, Bo;Wu, Lei
关键词:Nitrification; Denitrification; Paddy soil; Iron and manganese oxides
-
Water Chlorophyll a Estimation Using UAV-Based Multispectral Data and Machine Learning
作者:Zhao, Xiyong;Li, Yanzhou;Qiao, Xi;Zhao, Xiyong;Chen, Yongli;Zhao, Xiyong;Qiao, Xi;Qian, Wanqiang
关键词:chl-a; multiple regression; UAV; vegetation index; machine learning
-
Insights from the biogeographic approach for biocontrol of invasive alien pests: Estimating the ecological niche overlap of three egg parasitoids against Spodoptera frugiperda in China
作者:Zhao, Haoxiang;Xian, Xiaoqing;Yang, Nianwan;Zhang, Yongjun;Wan, Fanghao;Guo, Jianyang;Liu, Wanxue;Yang, Nianwan;Liu, Hui
关键词:Spodoptera frugiperda; Egg parasitoid; Biocontrol; Ensemble model; Potential suitable area
-
Antifungal activities of Bacillus velezensis FJAT-52631 and its lipopeptides against anthracnose pathogen Colletotrichum acutatum
作者:Deng, Ying-Jie;Chen, Zheng;Ruan, Chuan-Qing;Xiao, Rong-Feng;Liu, Bo;Chen, Mei-Chun;Wang, Jie-Ping;Deng, Ying-Jie;Lian, Heng-Ping;Chen, Mei-Chun;Wang, Jie-Ping
关键词:antifungal activity; biocontrol; Colletotrichum acutatum; lipopeptides; loquat
-
Cold Acclimation and Supercooling Capacity of Agasicles hygrophila Adults
作者:Pei, Yiming;Jin, Jisu;Wu, Qiang;Liang, Xiaocui;Lv, Chen;Guo, Jianying;Wu, Qiang
关键词:cold acclimation; supercooling; biological control; Agasicles hygrophila; Alternanthera philoxeroides