The positive effects of Camellia oleifera oil on lifespan in Caenorhabditis elegans
文献类型: 外文期刊
第一作者: Liu, Li
作者: Liu, Li;Zhou, Jiasi;Kong, Qingbo;Zhang, Jie;Wang, Heng;Xiang, Zhuoya;Chen, Tao;Zhou, Lijun;Feng, Shiling;Yang, Hongyu;Huang, Yan;Ding, Chunbang;Xu, Zhou;Xiang, Zhuoya
作者机构:
关键词: Camellia oleifera oil; Caenorhabditis elegans; Lifespan; Transcriptomics; Metabolomics
期刊名称:JOURNAL OF FUNCTIONAL FOODS ( 影响因子:5.6; 五年影响因子:5.3 )
ISSN: 1756-4646
年卷期: 2023 年 110 卷
页码:
收录情况: SCI
摘要: Aging is a major international concern that brings formidable socioeconomic and healthcare challenges. Therefore, this study aimed to investigate the positive effect of Camellia oleifera oil (CO) on the lifespan of C. elegans through transcriptome and metabolome analysis. The results demonstrated that CO direct significantly increased the lifespan and mean lifespan to 25.00 and 18.43 d, respectively, compared to the control group (15.95 d). Moreover, CO supplementation significantly improved the healthspan of C. elegans. Additionally, CO altered the transcription levels of genes involved in longevity regulating pathway and activated stress resistance pathway and influenced the levels of metabolic biomarkers related to galactose metabolism. Additionally, CO significantly reduced the content of ROS and MDA in C. elegans by 21.54% and 42.40%, respectively. Together, the study highlights the potential of CO in promoting lifespan and improving the health status, which shall facilitate its further development in the food and pharmaceutical industries.
分类号:
- 相关文献
作者其他论文 更多>>
-
Molecular characterizations of TLR1 and TLR2 in Qihe crucian carp (Carassius auratus) and responses to stimulations of Aeromonas hydrophila and TLR ligands
作者:Kong, Xianghui;Tang, Hairong;Kong, Xianghui;Zhu, Yachen;Zhang, Jie;Li, Chunjing;Zhao, Xianliang;Pei, Chao;Zhou, Yong;Zeng, Lingbing
关键词:Toll-like receptor 1; Toll-like receptor 2; Immune response; Toll-like receptor ligand; Qihe crucian carp Carassius auratus
-
Wheat TaSnRK2.10 phosphorylates TaERD15 and TaENO1 and confers drought tolerance when overexpressed in rice
作者:Zhang, Yanfei;Li, Yuying;Wang, Chenyang;Zhang, Yanfei;Wang, Jingyi;Li, Yuying;Zhang, Zihui;Yang, Lili;Wang, Min;Zhang, Yining;Zhang, Jie;Li, Chaonan;Li, Long;Jing, Ruilian;Mao, Xinguo;Zhang, Zihui;Zhang, Yining;Mao, Xinguo;Zhang, Jie;Reynolds, Matthew P.
关键词:
-
Preparation of chitooligosaccharides with a low degree of polymerization and anti-microbial properties using the novel chitosanase AqCsn1
作者:Xia, Chengyao;Qi, Mengyi;Wang, Yanxin;Zhang, Yue;Yang, Yiheng;Hu, Zejia;Du, Xin;Yu, Kuai;Huang, Yan;Li, Zhoukun;Ye, Xianfeng;Cui, Zhongli;Li, Ding;Li, Ding;Li, Ding;Zhao, Yuqiang
关键词:Chitosanase; Chitosan; Chitooligosaccharides; Agricultural diseases
-
Transcriptome Analysis Identifies Novel Genes Associated with Low-Temperature Seed Germination in Sweet Corn
作者:Xiao, Yingni;Chen, Mei;Zheng, Nannan;Xu, Zhuoyi;Zhang, Jie;Hu, Xinmin;Li, Li;Gu, Riliang;Du, Xuemei;Wang, Jianhua;Xiao, Yingni
关键词:sweet corn; seed vigor; low temperature germination capacity; transcriptome sequencing
-
Inhibition mechanism of trans-resveratrol on thermally induced trans fatty acids in peanut oil
作者:Li, Tian;Guo, Qin;Qu, Yang;Liu, Hongzhi;Liu, Li;Wang, Qiang;Zhang, Yu
关键词:Mechanism; Trans -resveratrol; Peanut oil; Trans fatty acids
-
Engineering Cupriavidus necator H16 for heterotrophic and autotrophic production of myo-inositol
作者:Wang, Xiaolu;Wang, Kaikai;Wang, Lei;Luo, Huiying;Wang, Yaru;Wang, Yuan;Tu, Tao;Qin, Xing;Su, Xiaoyun;Bai, Yingguo;Yao, Bin;Huang, Huoqing;Zhang, Jie;Wang, Lei
关键词:Cupriavidus necator; Metabolic engineering; Myo-inositol; Renewable feedstocks; CO2
-
Genome wide identification of GDSL gene family explores a novel GhirGDSL26 gene enhancing drought stress tolerance in cotton
作者:Liu, Jiajun;Liu, Jiangna;Wang, Heng;Xu, Yanchao;Hou, Yuqing;Wang, Yuhong;Zhou, Zhongli;Zheng, Jie;Liu, Fang;Cai, Xiaoyan;Khan, Aziz;Zheng, Jie;Zheng, Jie;Cai, Xiaoyan;Liu, Fang
关键词:Cotton; GDSL gene; Drought resistance; Functional identification