Molecular characterisation, temporal expression and involvement of ANGPTL4 in fat deposition in Muscovy ducks

文献类型： 外文期刊

第一作者： Zhu, J.

作者： Zhu, J.;Zhu, J.;Zhu, J.;Zhu, J.;Lyu, W.;Wang, W.;Ma, L.;Yang, H.;Xiao, Y.;Lu, L.

作者机构：

关键词： Muscovy ducks; ANGPTL4; fat deposition; gene expression; liver; abdominal fat

期刊名称：BRITISH POULTRY SCIENCE （ 影响因子：1.892； 五年影响因子：2.429 ）

ISSN： 0007-1668

年卷期： 2022 年 63 卷 6 期

页码：

收录情况： SCI

摘要： 1. Angiopoietin-like protein 4 (ANGPTL4) plays a key role in promoting fat metabolism and reducing blood lipid. This study characterised the ANGPTL4 gene in Muscovy ducks (Cairina moschata) and investigated its potential functions in fat metabolism in Muscovy ducks. 2. The Muscovy duck ANGPTL4 cDNA was successfully cloned for the first time, showing a length of 2591 bp. After phylogenetic analysis by RT-qPCR analysis, it was found that the ANGPTL4 gene of Anas platyrhynchos shared the highest sequence similarity with that of Muscovy ducks. 3. The ANGPTL4 gene was commonly expressed in 23 different tissues with the highest expression in the abdominal fat in Muscovy ducks. A significant association was observed between abdominal fat percentage (AFP) and the mRNA expression of the ANGPTL4 gene. Moreover, Muscovy ducks showed a peak of ANGPTL4 expression in the liver and abdominal fat at 1-2 weeks old. 4. These findings suggest that the ANGPTL4 gene is related to fat deposition and regulation in Muscovy ducks.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序