Supplementation of quinoa peptides alleviates colorectal cancer and restores gut microbiota in AOM/DSS-treated mice
文献类型: 外文期刊
第一作者: Fan, Xin
作者: Fan, Xin;Guo, Huimin;Teng, Cong;Yang, Xiushi;Qin, Peiyou;Ren, Guixing;Fan, Xin;Ren, Guixing;Guo, Huimin;Fan, Xin;Blecker, Christophe;Guo, Huimin;Richel, Aurore;Zhang, Lizhen;Ren, Guixing
作者机构:
关键词: Quinoa protein hydrolysate; Gastrointestinal digestion; Short chain fatty acids; Microbial dysbiosis; Colon cancer
期刊名称:FOOD CHEMISTRY ( 影响因子:8.8; 五年影响因子:8.6 )
ISSN: 0308-8146
年卷期: 2023 年 408 卷
页码:
收录情况: SCI
摘要: Quinoa protein hydrolysate has been previously reported to exert anti-cancer effects in cultured colon cancer cells. Here, we investigated the effect of quinoa protein and its hydrolysate on an azoxymethane/dextran sulfate sodium (AOM/DSS)-induced mouse model of colorectal cancer (CRC) and examined its underlying mechanism using gut microbiota analysis and short chain fatty acids (SCFAs) production analysis. Our results showed that quinoa protein or its hydrolysate mitigated the clinical symptoms of CRC and increased SCFAs contents in colon tissues. Moreover, administration of quinoa protein or its hydrolysate partially alleviated gut microbiota dys-biosis in CRC mice by decreasing the abundance of pathogenic bacteria and increasing the abundance of pro-biotics. Additionally, PICRUSt analysis revealed that the functional profile of gut microbiota in the quinoa protein treated groups was more similar to that of the control group. These findings indicated that the modu-lation of gut microbiota by quinoa protein diet intervention may ameliorate AOM/DSS-induced CRC.
分类号:
- 相关文献
作者其他论文 更多>>
-
Synchronous fluorescence detection of nitrite in meat products based on dual-emitting dye@MOF and its portable hydrogel test kit
作者:Deng, Siyang;Liu, Junmei;Han, Dong;Zhang, Chunhui;Yang, Xinting;Liu, Huan;Yang, Xinting;Liu, Huan;Deng, Siyang;Liu, Junmei;Blecker, Christophe
关键词:Luminescent metal organic framework; Dual-mode detection; On-spot visualization; NO2-; Rh6G@UIO-66-NH2
-
The gluten structure, starch digestibility and quality properties of pasta supplemented with native or germinated quinoa flour
作者:Xing, Bao;Zhang, Zhuo;Zhu, Manli;Teng, Cong;Ren, Guixing;Qin, Peiyou;Xing, Bao;Zhang, Zhuo;Zhu, Manli;Zhang, Lizhen;Zou, Liang;Ren, Guixing;Liu, Rui;Yang, Xiushi;Ren, Guixing;Qin, Peiyou
关键词:Pasta; Quinoa; Germination; Gluten; In vitro starch digestibility; Quality
-
Effects of extrusion on structural properties, physicochemical properties and in vitro starch digestibility of Tartary buckwheat flour
作者:Zhang, Zhuo;Zhu, Manli;Xing, Bao;Liang, Yongqiang;Li, Mengzhuo;Fan, Xin;Ren, Guixing;Qin, Peiyou;Zhang, Zhuo;Zhu, Manli;Xing, Bao;Liang, Yongqiang;Zhang, Lizhen;Zou, Liang;Ren, Guixing;Zhang, Lizhen;Qin, Peiyou
关键词:Tartary buckwheat; Extrusion; Starch structure; Physicochemical properties; In vitro starch digestibility
-
Preparation of cellulose nanocrystals from purple sweet potato peels by ultrasound-assisted maleic acid hydrolysis
作者:Zhu, Shunshun;Sun, Hongnan;Mu, Taihua;Li, Qiang;Richel, Aurore
关键词:Cellulose nanocrystals; Ultrasound -assisted maleic acid hydrolysis; Zeta potential; Chemical structure; Thermal stability; Crystallinity
-
Innovative incentives can sustainably enhance the achievement of straw burning control in China
作者:Wang, Shu;Yin, Changbin;Li, Fuduo;Wang, Shu;Richel, Aurore;Yin, Changbin
关键词:Editor; Jacopo Bacenetti; Straw burning ban; Transferred payment; Carbon trading; China
-
Barter mode: The institutional innovation for affordable and clean energy (SDG7) in rural China
作者:Wang, Shu;Yin, Changbin;Yang, Xiaomei;Wang, Shu;Richel, Aurore;Yin, Changbin
关键词:Barter mode; Straw pellet; SDG7; China
-
Genome-Wide Survey Reveals the Microsatellite Characteristics and Phylogenomic Relationships of Dictyosoma burgeri (Zoarcales, Perciformes)
作者:Liu, Lu;Fan, Xin;Li, Chunhou;Li, Chunhou;Liu, Qi;Chen, Zhi
关键词:Phylogenomic; Genome survey; Bony fish; Mitochondrial genome