Herbicide prometryn adversely affects the development and reproduction of Tigriopus japonicus by disturbing the ecdysone signal pathway and chitin metabolic pathway
文献类型: 外文期刊
第一作者: Wang, Dong
作者: Wang, Dong;Ru, Shaoguo;Zhang, Zhenzhong;Li, Yuejiao;Wang, Jun;Yang, Guangxin
作者机构:
关键词: Prometryn; Tigriopus japonicus; Life-history traits; 20-hydroxyecdysone; Chitin metabolic pathway
期刊名称:AQUATIC TOXICOLOGY ( 影响因子:4.5; 五年影响因子:5.2 )
ISSN: 0166-445X
年卷期: 2023 年 254 卷
页码:
收录情况: SCI
摘要: Prometryn, a widely used triazine herbicide in agriculture and aquaculture, has been commonly detected in marine environments, but its effects on the marine copepod are unknown. In this study, marine copepod Tigriopus japonicus was chronically exposed to environmentally relevant concentrations of prometryn to investigate its impacts and potential mechanism of action. The results showed that 0.5, 5, and 50 mu g/L prometryn delayed the first spawning time and hatching time, reduced the fecundity, and inhibited the population growth rate. Moreover, exposure to 0.5, 5 and 50 mu g/L prometryn decreased food ingestion, the content of C and N elements, nutrient accumulation and body size, but increased the content of 20-hydroxyecdysone (20E). Transcriptome analysis showed that 50 mu g/L prometryn down-regulated 1431 genes, which were mainly enriched in lysosome pathway and chitin binding and cuticle construction process. The results of qRT-PCR showed that the expression of key genes involved in juvenile hormone synthesis and chitin metabolic pathways were also inhibited after prometryn exposure. Molecular docking revealed that prometryn could bind to ecdysone receptor (EcR) and UDP-N-acetylglucosamine pyrophosphorylase (UAP), components of the ecdysteroid nuclear receptor complex. Therefore, environmental relevant prometryn delayed the molting and development of T. japonicus by disrupting the ecdysone signal pathway and chitin metabolic pathway through binding to EcR and UAP. This study provides new insights into toxic effects and molecular mechanisms of prometryn on marine copepods.
分类号:
- 相关文献
作者其他论文 更多>>
-
The host protein CALCOCO2 interacts with bovine viral diarrhoea virus Npro, inhibiting type I interferon production and thereby promoting viral replication
作者:Wang, Song;Wang, Song;Ma, Xiaomei;Guo, Jin;Aizaz, Muhammad;Li, Fangxu;Wang, Jun;Wang, Hongmei;He, Hongbin;Wei, Ran
关键词:BVDV; Npro; CALCOCO2; IRF3; IFN-I; innate immunity
-
Ripening induced degradation of pectin and cellulose affects the medium-and short-wave infrared drying characteristics of mulberry
作者:Wang, Kunhua;Li, Qingyuan;He, Peiyun;Jia, Xiaoran;Ren, Wenxin;Wang, Jun;Xu, Huaide;Xue, Yuan;Yang, Zhongqiang
关键词:Mulberry density; Ripeness grading; Physicochemical properties; Pectin fraction; Hemicellulose and cellulose; Nanostructure; Monosaccharides composition; Drying characteristics
-
Patterns and determinants of nitrification and denitrification potentials across 24 rice paddy soils in subtropical China
作者:Wang, Jun;Zhang, Wenju;Wu, Lei;Lv, Lu;Hu, Ronggui;Ma, Haiyang;Liu, Bo;Wu, Lei
关键词:Nitrification; Denitrification; Paddy soil; Iron and manganese oxides
-
Comparison of muscle structure and transcriptome analysis reveals the mechanism of growth variation in Yangtze sturgeon (Acipenser dabryanus)
作者:Li, Qingzhi;Chen, Yeyu;Wu, Xiaoyun;Liu, Ya;Lai, Jiansheng;Song, Mingjiang;Li, Feiyang;Li, Pengcheng;He, Bin;Wang, Bin;Yan, Tao;Gong, Quan;Li, Qingzhi;Wang, Bin;Gong, Quan;Wang, Jun;Wang, Jun
关键词:Acipenser dabryanus; Growth difference; GH/IGF axis; Myogenic regulatory factor; Cell cycle
-
The Effect of Banana Rhizosphere Chemotaxis and Chemoattractants on Bacillus velezensis LG14-3 Root Colonization and Suppression of Banana Fusarium Wilt Disease
作者:Yang, Lihua;Zhou, You;Guo, Lijia;Yang, Laying;Wang, Jun;Liang, Changcong;Huang, Junsheng
关键词:chemotaxis; Bacillus velezensis; root exudates; citric acid; glycine; banana Fusarium wilt disease; biocontrol
-
Spatiotemporal variations and driving factors for potential wind erosion on the Mongolian Plateau
作者:Wei, Xianhua;Wu, Xiaodong;Wang, Dong;Wu, Tonghua;Li, Ren;Hu, Guojie;Zou, Defu;Ma, Xin;Liu, Yadong;Yan, Xuchun;Fan, Xiaoying;Cao, Xiaoyan;Wei, Xianhua;Wu, Xiaodong;Wang, Dong;Ma, Xin;Liu, Yadong;Yan, Xuchun;Fan, Xiaoying;Cao, Xiaoyan;Wu, Tonghua;Bai, Keyu;Bai, Keyu;Dashtseren, Avirmed;Wu, Xiaodong
关键词:Soil erosion; Land cover type; Climate change; Deserti fication
-
Efficient acquisition of high-purity cyanidin-3-O-glucoside from mulberry fruits: An integrated process of ATPS whole-cell transformation and semi-preparative HPLC purification
作者:Li, Yi-Tong;Huang, Ting;Wang, Jin-Zheng;Yan, Cheng-Hai;Gong, Lu-Chan;Wu, Fu-An;Wang, Jun;Gong, Lu-Chan;Wu, Fu-An;Wang, Jun
关键词:Aqueous two-phase system; Cyanidin-3-O-glucoside; Cyanidin-3-O-rutinoside; Whole cell; Mulberry red pigment; Semi-preparative HPLC