Simultaneous determination of enantiomer residues of metalaxyl and its metabolite metalaxyl acid in animal muscle tissues by chiral liquid chromatography-tandem mass spectrometry
文献类型: 外文期刊
第一作者: Zhou, Hao
作者: Zhou, Hao;Shan, Qi;Zhao, Cheng;Zheng, Guangming;Li, Lichun;Ma, Lisha;Yin, Yi;He, Limin;Zhang, Meiyu;Xu, Feng
作者机构:
关键词: Metalaxyl; Metabolite residue; Solid phase extraction; Chiral LC-MS/MS; Muscle tissues; Stereoselective analysis
期刊名称:FOOD CHEMISTRY ( 影响因子:8.8; 五年影响因子:8.6 )
ISSN: 0308-8146
年卷期: 2024 年 435 卷
页码:
收录情况: SCI
摘要: The toxicity of the two enantiomers of metalaxyl is significantly different and, for food safety concerns, stereoselective analysis of its residues is extremely important in animal muscle tissues. Herein, a simple, sensitive and reproducible method for the simultaneous stereoselective analysis of metalaxyl and its metabolite metalaxyl acid in animal-derived foods has been established based on mixed-mode anion exchange solid phase extraction and chiral liquid chromatography-tandem mass spectrometry. Under the optimized separation and sample pretreatment conditions, good linearity (r > 0.99) was obtained for four target analytes in four animal muscle tissues including bovine, chicken, swine and fish. Mean recoveries of all enantiomers in muscle tissue samples were 89.5-110.3 % with relative standard deviations below 12.4 %. The limits of quantification of the analytes were 0.3-1.0 mu g/kg. The proposed method provides an effective means to monitor the enantiomer residues in real samples whether using highly active R-metalaxyl or racemic mixture drugs.
分类号:
- 相关文献
作者其他论文 更多>>
-
Determination of trace vancomycin in edible animal tissues and assessment of matrix effects
作者:Chen, Qianqian;Chen, Ruqing;Wu, Zhanghe;Liu, Yahong;He, Limin;Zhou, Hao;Chen, Xing;Liu, Yahong;Zhou, Hao
关键词:Vancomycin; Edible animal tissues; Surface molecularly imprinted solid-phase; extraction; Matrix effects; Glycerophospholipids; Liquid chromatography-tandem mass; spectrometry
-
Application of melatonin delays lignification in postharvest water bamboo shoots in association with energy metabolism
作者:Yang, Baiqi;Liu, Ruihai;Li, Bin;Han, Yanchao;Gao, Haiyan;Liu, Ruiling;Xiao, Shangyue;Chen, Hangjun;Han, Yanchao;Gao, Haiyan;Liu, Ruiling;Xiao, Shangyue;Chen, Hangjun;Han, Yanchao;Gao, Haiyan;Liu, Ruiling;Xiao, Shangyue;Chen, Hangjun;Han, Yanchao;Gao, Haiyan;Liu, Ruiling;Xiao, Shangyue;Chen, Hangjun;Han, Yanchao;Gao, Haiyan;Liu, Ruiling;Xiao, Shangyue;Chen, Hangjun;Xu, Feng;Liu, Ruihai
关键词:Water bamboo shoot; Melatonin; Energy metabolism; ATP; Pyridine nucleotide
-
The structure-function relationships of pectins separated from three citrus parts: Flavedo, albedo, and pomace
作者:Zhang, Lin;Cui, Jiefen;Liu, Dan;Zhao, Cheng;Zheng, Jinkai;Zhang, Lin;Cui, Jiefen;Zhao, Shaojie;Zheng, Jinkai
关键词:Citrus; Pectin; Different parts; Chemical structure; Functional property
-
Tensile and shear mechanical properties of laver (Porphyra yezoensis Ueda)
作者:Lu, Wei;Li, Xiuchen;Zhang, Guochen;Tang, Jiahong;Ni, Shang;Zhao, Cheng;Sun, Zhenyin;Zhang, Hanbing;Zhang, Qian;Mu, Gang;Lu, Wei;Li, Xiuchen;Zhang, Guochen;Zhang, Hanbing;Zhang, Qian;Mu, Gang;Li, Xiuchen;Zhang, Guochen;Zhang, Hanbing;Zhang, Qian;Mu, Gang;Mu, Gang;Mu, Gang;Mu, Gang
关键词:Laver; Mechanical properties; Tensile force; Shear force; Tensile energy; Shear energy; Loading rate; Harvest time; Origin
-
Exploring Effects of Exogenous Selenium on the Growth and Nutritional Quality of Cabbage (Brassica oleracea var. capitata L.)
作者:Yu, Li;Chen, Qiangwen;Liao, Xiaoli;Chao, Wei;Zhang, Weiwei;Liao, Yongling;Ye, Jiabao;Xu, Feng;Chen, Qiangwen;Cong, Xin;Yang, Xiaoyan;Cong, Xin;Cheng, Shuiyuan;Qian, Hua;Zhao, Yang
关键词:Brassica oleracea; selenite; nutrient quality; Se speciation; antioxidant enzymes
-
Characterization of Brucella abortus Mutant A19mut2, a Potential DIVA Vaccine Candidate with a Modification on Lipopolysaccharide
作者:Abdelgawad, Hosny Ahmed;Lian, Zhengmin;Yin, Yi;Fang, Tian;Tian, Mingxing;Yu, Shengqing;Abdelgawad, Hosny Ahmed;Yu, Shengqing
关键词:Brucella abortus; vaccine; differential diagnosis; lipopolysaccharide; modification
-
Physiological and Biochemical Properties of Cotton Seedlings in Response to Cu2+ Stress
作者:Zhou, Hao;Zhao, Gang;Wang, Pei-Pei;Gao, Jun-Shan;Zhou, Ke-Hai;Yang, Dai-Gang;Ma, Xiong-Feng
关键词:copper; cotton; tolerance; antioxidants; reactive oxygen species