文献类型： 外文期刊
第一作者： Ji, Kai-Long
作者： Ji, Kai-Long;GongPan, Pian-Chou;Sun, Peng;Lu, Jian-Mei;Tang, Yan-Qing;Guo, Zheng-Yang;Li, Ting;Dai, Meng-Yuan
作者机构：
关键词： Glycosmis lucida; geranylated sulfonyl amides; glylucidamides; Th17 differentiation; ROR gamma t
期刊名称：CHEMISTRY & BIODIVERSITY （ 影响因子：2.9； 五年影响因子：2.8 ）
ISSN： 1612-1872
年卷期： 2023 年 20 卷 6 期
页码：
收录情况： SCI
摘要： Chemical investigation of medicinal plant Glycosmis lucida Wall. ex C. C. Huang leaves led to the production of ten compounds (1-10), including two previously unreported geranylated sulfurcontaining amides (1 and 2) and eight known ones (3-10). Structural characterization was carried out using comprehensive spectroscopic methods including NMR, MS and CD. The inhibitory effects of all isolates on Th17 differentiation were evaluated, of which compounds 1 and 6 significantly inhibited Th17 differentiation with IC50 values of 0.36 and 1.30 mu M, respectively, while both 1 and 6 failed to bind to retinoic acid-related orphan receptor gamma t (ROR gamma t), suggesting that their inhibition of Th17 differentiation is independent of ROR gamma t.
分类号：
- 相关文献
作者其他论文 更多>>
-
Growth arrest and DNA damage-inducible 45 ab gene targeted by miR-20b-5p executes the inflammation and apoptosis by regulating MAPK and NF-κB pathways in black rockfish
作者：Gao, Chengbin;Cai, Xin;Zhu, Ying;Cao, Min;Li, Chao;Gao, Chengbin;Cai, Xin;Ma, Le;Sun, Peng
关键词：Ss _ gadd45ab; Inflammation; Apoptosis; Black rockfish; Regulatory mechanism
-
Weighted Gene Co-Expression Network Analysis Reveals Hub Genes for Fuzz Development in Gossypium hirsutum
作者：Jiao, Yang;Xu, Kaixiang;Zhao, Jieyin;Li, Shengmei;Geng, Shiwei;Gao, Wenju;Deng, Xiaojuan;Chen, Quanjia;Qu, Yanying;Long, Yilei;Li, Chunpin;Zhao, Fuxiang;Sun, Peng
关键词：WGCNA; fuzz; hub genes; RNA-Seq; Gossypium hirsutum
-
GWAS-assisted genomic prediction of cadmium accumulation in maize kernel with machine learning and linear statistical methods
作者：Yan, Huili;Xu, Wenxiu;Dai, Changhua;Kimani, Wilson;Zhang, Hezifan;Li, Ting;Ma, Mi;Guo, Hanyao;Dai, Changhua;Kimani, Wilson;Zhang, Hezifan;Li, Ting;He, Zhenyan;Xie, Jianyin;Wang, Feng;Yu, Yijun;Hao, Zhuanfang;He, Zhenyan
关键词：Genomic prediction; Maize Cd accumulation; Machine learning; Linear statistical methods
-
Soil potentially toxic element pollution at different urbanization intensities: Quantitative source apportionment and source-oriented health risk assessment
作者：Li, Xinyun;Li, Lulu;Li, Ting;An, Ji;Pu, Yulin;Jia, Yongxia;Liu, Xiaojing;Li, Yun;Zhou, Zijun;Zhang, Shirong;Xu, Xiaoxun;Wang, Guiyin
关键词：Potentially toxic elements; Urbanization intensity; Source apportionment; Risk assessment
-
Lack of Known Target-Site Mutations in Field Populations of Ostrinia furnacalis in China from 2019 to 2021
作者：Gong, Youhui;Xiu, Xiaojian;Hou, Maolin;Li, Ting;Desneux, Nicolas
关键词：Ace 1 gene; diamide insecticides; genotype; insecticide susceptibility; RyR gene; L1014F mutation
-
Variation in glucosinolates and the formation of functional degradation products in two Brassica species during spontaneous fermentation
作者：Qinghang, Wu;He, Chengyun;Zhao, Shengming;Qinghang, Wu;Zhang, Chengcheng;Zhang, Jianming;Xin, Xiaoting;Li, Ting;Liu, Daqun;Zhang, Chengcheng;Zhang, Jianming;Liu, Daqun
关键词：Fermentation; Cauliflower; Broccoli; Glucosinolates; Degradation
-
Effect of substituting steam-flaked corn for course ground corn on in vitro digestibility, average daily gain, serum metabolites and ruminal volatile fatty acids, and bacteria diversity in growing yaks
作者：Liu, Ying;Hao, Lizhuang;Liu, Junhao;Sun, Peng;Degen, Allan
关键词：Steam -flaked corn; Yaks; Growth performance; Rumen bacteria
