Genetic polymorphisms in immune- and inflammation-associated genes and their association with bovine mastitis resistance/susceptibility
文献类型: 外文期刊
第一作者: Khan, Muhammad Zahoor
作者: Khan, Muhammad Zahoor;Wang, Jingjun;Ma, Yulin;Chen, Tianyu;Ma, Mei;Cao, Zhijun;Liu, Shuai;Khan, Muhammad Zahoor;Ullah, Qudrat;Khan, Ibrar Muhammad;Khan, Adnan
作者机构:
关键词: bovine mastitis; immunity and inflammation; genetic markers; polymorphisms; SCS; SCC; inflammatory cytokines
期刊名称:FRONTIERS IN IMMUNOLOGY ( 影响因子:7.3; 五年影响因子:8.0 )
ISSN: 1664-3224
年卷期: 2023 年 14 卷
页码:
收录情况: SCI
摘要: Bovine mastitis, the inflammation of the mammary gland, is a contagious disease characterized by chemical and physical changes in milk and pathological changes in udder tissues. Depressed immunity and higher expression of inflammatory cytokines with an elevated milk somatic cell count can be observed during mastitis in dairy cattle. The use of somatic cell count (SCC) and somatic cell score (SCS) as correlated traits in the indirect selection of animals against mastitis resistance is in progress globally. Traditional breeding for mastitis resistance seems difficult because of the low heritability (0.10-0.16) of SCC/SCS and clinical mastitis. Thus, genetic-marker-selective breeding to improve host genetics has attracted considerable attention worldwide. Moreover, genomic selection has been found to be an effective and fast method of screening for dairy cattle that are genetically resistant and susceptible to mastitis at a very early age. The current review discusses and summarizes the candidate gene approach using polymorphisms in immune- and inflammation-linked genes (CD4, CD14, CD46, TRAPPC9, JAK2, Tf, Lf, TLRs, CXCL8, CXCR1, CXCR2, C4A, C5, MASP2, MBL1, MBL2, LBP, NCF1, NCF4, MASP2, A2M, and CLU, etc.) and their related signaling pathways (Staphylococcus aureus infection signaling, Toll-like receptor signaling, NF-kappa B signaling pathway, Cytokine-cytokine receptor, and Complement and coagulation cascades, etc.) associated with mastitis resistance and susceptibility phenotypic traits (IL-6, interferon-gamma (IFN-gamma), IL17, IL8, SCS, and SCC) in dairy cattle.
分类号:
- 相关文献
作者其他论文 更多>>
-
Hybrid bismuth oxide-graphine oxide nanomaterials improve the signal-to-noise response of small molecules analyzed by matrix assisted laser desorption ionization-time-of-flight mass spectrometry
作者:Tang, Xuemei;Chen, Zhiting;Chen, Yan;Jiang, Xunyuan;Zhu, Fuwei;Liu, Shuai;Wan, Kai;Tang, Xuemei;Zhu, Fuwei;Wan, Kai;Chen, Yan;Liu, Shuai;Wan, Kai
关键词:MALDI; Small molecules; Nanomaterial; Time-of-flight; Mass spectrometry
-
Enhancing Metabolism and Milk Production Performance in Periparturient Dairy Cattle through Rumen-Protected Methionine and Choline Supplementation
作者:Huang, Bingjian;Khan, Muhammad Zahoor;Kou, Xiyan;Chen, Yinghui;Liang, Huili;Chai, Wenqiong;Wang, Changfa;Huang, Bingjian;Khan, Muhammad Zahoor;Ullah, Qudrat;Khan, Nadar;Khan, Adnan
关键词:dairy cattle; periparturient period; RPM; RPC; milk production; metabolism; nitrogen utilization
-
Overview of the effect of rumen-protected limiting amino acids (methionine and lysine) and choline on the immunity, antioxidative, and inflammatory status of periparturient ruminants
作者:Khan, Muhammad Zahoor;Liu, Shuai;Ma, Yulin;Ma, Mei;Wang, Jingjun;Xiao, Jianxin;Chen, Tianyu;Cao, Zhijun;Khan, Muhammad Zahoor;Ullah, Qudrat;Khan, Ibrar Muhammad;Khan, Adnan
关键词:oxidative stress; periparturient period; ruminants; antioxidants; immunity; limiting amino acids
-
Dynamic changes of the gut microbial colonization in preterm infants with different time points after birth
作者:Khan, Adnan;Gao, Fei;Mi, Hongying;Gao, Fei;Hu, Qi;Gu, Xia;Li, Sitao;Hao, Hu;Ma, Fei;Qu, LiuHong;Dai, Yiheng
关键词:preterm infants; gut microbiota; Bifidobacterium; Escherichia coli; Klebsiella
-
Combination of CNP, MT and FLI during IVM Significantly Improved the Quality and Development Abilities of Bovine Oocytes and IVF-Derived Embryos
作者:Zhang, Peipei;Yang, Baigao;Xu, Xi;Zhang, Hang;Feng, Xiaoyi;Hao, Haisheng;Du, Weihua;Zhu, Huabin;Zhao, Xueming;Li, Shujing;Yu, Wenli;Khan, Adnan;Umer, Saqib
关键词:bovine; oocytes; ovum pich up; C-type natriuretic peptide; melatonin; FLI (IGF plus FGF plus LIF)
-
Ecological risks of microplastics contamination with green solutions and future perspectives
作者:Khan, Aziz;Wang, Jing;Zhao, Ze-Ying;Wang, Peng-Yang;Khan, Adnan;Wang, Wei;Li, Meng-Ying;Zhang, Wei;Xiong, You-Cai;Jie, Zheng;Nepal, Jaya;Ullah, Najeeb;Ahmad, Wiqar;Elsheikh, Mohammad Soliman
关键词:Environmental pollution; micro-plastics; Greenhouse gases emission; Soil contaminants; Soil-plant health
-
Dietary replacement of inorganic trace minerals with lower levels of organic trace minerals leads to enhanced antioxidant capacity, nutrient digestibility, and reduced fecal mineral excretion in growing-finishing pigs
作者:Xiong, Yunxia;Cui, Bailei;He, Zhentao;Liu, Shuai;Wu, Qiwen;Yi, Hongbo;Jiang, Zongyong;Hu, Shenglan;Wang, Li;Zhao, Fei
关键词:organic trace minerals; growing-finishing pigs; antioxidant capacity; apparent nutrient digestibility; fecal mineral excretion